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20th Anniversary logo
   

20 years of history

Founders
Picture at right shows deans and
directors who have guided the
BioTechnology Institute since its
inception. From left to right are
Michael Flickinger, first BTI director;
CBS dean Bob Elde; Ken Valentas,
current BTI director; former CBS
dean Pete Magee; founding dean
Richard Caldecott; and Victor
Bloomfield, former interim dean of
the Graduate School and former head
of the biochemistry department.

The concept for BTI (formerly BPTI) was proposed by Prof. Vic Bloomfield and Dean Richard Caldecott in 1983. Space was allocated in 1984, and a search for the first director was initiated. Prof. Michael Flickinger was hired as director in 1985. This then became the year in which the concept became operational and from which the chronology begins. Since 1985 there have been two directors and three deans involved in the administration of the institute.

BRC oldBiotechnology Resource Center
The BTI was chartered by the state to be its biotechnology initiative. It has a commitment to provide state-of-the-art equipment and facilities to support the research efforts of faculty and companies, both small and large, to help catalyze the development of a biotechnology industry in Minnesota.

BRC currentBTI has dedicated considerable effort and resources to convert a sub-standard space in the basement of Gortner Lab to the Biotechnology Resource Center (BRC), which is the cornerstone of Biodale. Over the years, there have been significant contributions from companies such as ABEC, Inc., Fisher Rosemount, Hosakawa-Bepex and others.

Training grantTraining grant
Starting in 1990, the BTI was successful in pursuing a 5-year, cross-disciplinary biotechnology grant from the NIH. This was renewed in 1995 and again in 2000-2005 for $2.3 million. Over the past 15 years, this grant has provided financial support for over 100 graduate students who have participated in the program. Some 67 students have completed their Ph.D. degrees in disciplines such as Biochemistry, Microbiology, Chemical Engineering and Materials Science, Genetics, Chemistry, Computer Science, Biomedical Engineering, Plant Sciences, Mathematics, Health Informatics and Electrical Engineering. Of these, 42 have taken industrial positions in biotechnology, 20 are in academia, and 5 have gone on to medical careers. The BTI has provided significant administrative and financial support to sustain the grant.

Seed grants
A research university lives on grants to support its graduate students and post-doctoral associates. Competition for grants is very keen, and the funds available to the granting agencies have not kept pace with the expanding research base in biotechnology -- more people competing for fewer resources. To provide our faculty a competitive edge, the BTI began making seed grants available in 1993. These grants are intended to fund one year of research with the goal of generating sufficient preliminary data to increase the odds of success in grant applications. This has in fact been the case, but more importantly, it has provided encouragement for the faculty to try new ideas and move into areas with potential for seminal discovery.

Global exchange

Exchange programs
Biotechnology is a global enterprise. In 1996, BTI established a formal exchange program with the Nara Institute of Science and Technology (NAIST) in Japan. In 2001, a program was established with the Hochschule Wadenswill in Switzerland. Students and faculty on each side of these exchanges have experienced each other's culture and approach to biotechnology. An aggregate of over 100 students and faculty have been involved since inception.

1985
  • Michael Flickinger becomes founding director.
  • Prof. Friedrich Srienc hired as joint appointment: BPTI and Chemical Engineering and Material Science.
    1986
  • Prof. Robert Brooker hired as joint appointment: BPTI and Genetics and Cell Biology.
    1989
  • Prof. Gary Dunny hired as joint appointment: BPTI and Microbiology.
    1990
  • Prof. David Sherman hired as joint appointment: BPTI and Microbiology.
  • International Streptococcal Genetics Symposium.
    1992
  • Prof. Larry Wackett joins as joint appointment: BPTI and Biochemistry.
  • Ken Valentas becomes interim director.
    1995
  • Ken Valentas named permanent director.
    1996
  • Biorefinery Conference.
  • Mathematical Modeling in Biochemical Engineering Conference.
    1998
  • Prof. Michael Sadowsky joins as joint appointment: BPTI and Soil, Water and Climate.
  • Prof. Antony Dean hired as joint appointment: BPTI and Ecology, Evolution and Behavior.
    1999
  • Genomics Symposium.
    2000
  • Bioinformatics Symposium.
  • Novel Plants & Microbes of Environmental Biology Symposium in Nara, Japan.
    2001
  • Name changed to BioTechnology Institute.
  • Prof. Arkady Khodursky joins as joint appointment: BPTI and Biochemistry, Molecular Biology and Biophysics.
  • Biomaterials Symposium.
    2003
  • Prof. Romas Kazlauskas joins BTI as Assoc. Prof. Molecular Biology and Biophysics.
  • Research collaboration workshop with NAIST.
    2004
  • Profs. Daniel Bond, Wei-Shou Hu, Claudia Schmidt-Dannert and Mark Distefano all join BTI.
  • Joint Bioinformatics workshop with NAIST.
    2005
  • BTI celebrates 20 years.
  • Prof. Jeffrey Gralnick joins BTI as Assoc. Prof. Microbiology.
  • Symposium on biotechnology trends.
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