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Welcome to the University of Minnesota 's Biotechnology Training Program, supported by an NIGMS grant from the National Institute of Health. In place at the University of Minnesota since 1990, this program has brought together gifted graduate students and faculty trainers from many different disciplines to pursue unique and innovative research and educational programs that span the many facets of biotechnology. The goal of the training program is to provide students with opportunities that will enable them to identify themselves as biotechnologists. A salient feature of this program is its many educational activities aimed at integrating concepts from engineering and the biological and chemical sciences. Each year, this program financially sponsors sixteen select students from designated graduate programs and enriches their traditional studies by an additional emphasis on cross-disciplinary courses, collaborative research, industrial and global interactions, ethics training, and specialized retreats and seminars.
Welcome to the University of Minnesota 's Biotechnology Training Program, supported by an NIGMS grant from the National Institute of Health. In place at the University of Minnesota since 1990, this program has brought together gifted graduate students and faculty trainers from many different disciplines to pursue unique and innovative research and educational programs that span the many facets of biotechnology. The goal of the training program is to provide students with opportunities that will enable them to identify themselves as biotechnologists. A salient feature of this program is its many educational activities aimed at integrating concepts from engineering and the biological and chemical sciences. Each year, this program financially sponsors sixteen select students from designated graduate programs and enriches their traditional studies by an additional emphasis on cross-disciplinary courses, collaborative research, industrial and global interactions, ethics training, and specialized retreats and seminars.
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Trainee Requirements
United States citizenship or permanent residency, good academic standing, graduate student status, and an interest in cross-disciplinary training.
Consideration
Trainees are considered for application after they have been accepted to a specific graduate program and selected an advisor, normally done by the individual graduate programs. Candidates, most of them completing the first year of their Ph.D. programs, are nominated by their training grant faculty advisors for a position on the training grant during the spring semester. The candidate's ability to expand his or her intellectual horizon to new dimensions and to synthesize new knowledge from different disciplines will be used as a major factor for the selection process. In keeping with the philosophy of cross-disciplinary knowledge expansion, the committee strives to create a balance of students from different disciplines in the training prgram. In addition, priority of selection will be given to students who have chosen to pursue a Ph.D. degree in a discipline area other than the one in which they obtained their undergraduate or master's degree.
Prospective students
Students who are interested in the training program and who have not yet applied for a graduate program at the university may consult with the steering committee, administrative director, and program director regarding which graduate programs would be appropriate choices for their admission to the University of Minnesota. First year graduate students in participating departments may contact training faculty in their departments.
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The training program is divided into six areas of emphasis based upon the expertise of the trainers as well as the areas that we consider as critical to the future generation of scientists and engineers in biotechnology. These areas are used as a framework to organize workshops and focus areas for seminars.
(1) Structural Biology and Biomolecular Engineering
Trainers: Bates, Brooker (coordinator), Distefano, Kazlauskas, Kiehl, Kokkoli, McCormick, Musier-Forsyth, Schmidt-Dannert, Tranquillo
The research emphasis of this group is aimed at understanding the structural details of molecules and macromolecules and their interactions with synthetic materials. This type of work can lead to biotechnological applications in areas such as rational protein design, for novel specificity and functions, and engineering of novel biocomposite materials.
(2) Bioreaction Engineering
Trainers: Arriaga, Dean, Daoutidis (coordinator), Flickinger, Hu, Kazlauskas, Maynard, Sadowsky, Schmidt-Dannert, Srienc, Wackett
The expertise encompasses metabolic and genetic reaction networks and population dynamics. The research topics range from engineering novel biochemical pathways, alternating regulatory structures, constructing new microbial communities, and developing new environmental technologies.
(3) Bioinformatic Science and Engineering
Trainers: Arriaga, Distefano, Ellis, Hu, Kapur, Karypis, Kaznessis (coordinator), Kumar
This subgroup of trainers is formed to address a critical area in biotechnology, the development and utilization of new Bioinformatic tools for mining data generated using genomic and proteomic technologies.
(4) Genomic Science and Microbial Ecology
Trainers: Berman, Ellis, Hu, Kahn, Kapur, Karypis, Kazlauskas, Khodursky (coordinator), Maynard, McIvor, Phillips, Retzel, Sadowsky, Schmidt-Dannert, Schottel, Wackett
A diverse expertise exists in molecular biology and genomic technologies. The genomic work by this group encompasses eubacteria, yeast and fungi, plants and animals. The research ranges from genomic and EST sequencing to database design and physiological reaction modeling. Studies are pertinent in the areas of drug development and the biodegradation of pollutants.
(5) Complex Biological Systems
Trainers: Berman, Daoutidis (coordinator), O'Connor, Othmer, Phillips, Somers, Srienc, Tranquillo, Verfaillie, Sadowsky
A primary interest of this group is an understanding of processes that affect the biology of whole organisms or systems with organisms. These trainers are engaged in research projects related to the development of corn, carrots, legumes, C. elegans, or vertebrates. Work is also in progress to harness the advances in developmental biology for crop improvement, micropropagation, and engineering tissues including blood vessels and liver.
(6) Systems Engineering in Biology
Trainers: Brooker, Daoutidis, Dunny, Hu, Kapur, Karypis, Khodursky, Lipscomb, Musier-Forsyth, Othmer, Schmidt-Dannert, Schottel, Sadowsky (coordinator), Srienc, Tranquillo, Wackett
This group of trainers conducts research and training on systems approach to biology. We have an unusually large pool of expertise in this critical area of research and training for biotechnology. The work encompasses the genetic regulatory network at the single cell level, the interactions of pure and mixed populations with the environment, data mining, and mathematical modeling and competition.
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New for the Fall 2004 semester, the training program has created a course designed for the Biotechnology Training Grant trainees, entitled "Systems Analysis of Biological Processes." This three credit course is a lecture series conducted by training grant faculty and coordinated by Professor Wei-Shou Hu. This course is designed for graduate students from all of the different programs the training grant supports-life sciences, chemical and physical sciences, and engineering and focuses on the quantitative analysis of biological systems. The course aims to introduce methodology for analyzing data attained at a genomic level to their integration for interpreting physiological events. It emphasizes the conceptual appreciation of the quantification of molecular interplays which are the basis of "chemical processes" in living systems.
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Our training faculty and BTI maintain very strong ties to industry. Many trainees work on collaborative projects with industry. Many trainees attend the Cell and Tissue Reactor Engineering course offered by key trainers, which draws over 60 industrial scientists and engineers every year. All have had a very positive impact on the training experience of the students. Overall, we are very satisfied with the trainees' industrial interactions through luncheons with visitors, seminars at industrial sites , and plant tours and retreats. Trainees are invited to an occasional luncheon with entrepreneurial scientists from the start-up companies in the University's industrial incubator facility (BTI-Technology Development Laboratories). Many of those scientists from the Technology Development Laboratories companies are the original inventors of the ideas they are trying to commercialize. Meeting with them and hearing about their quest for venture capital, and balancing intellectual pursuit and the business reality adds a very different dimension to the trainees' conception of research.
Another important component of our trainee's industrial interaction is through the internship. In 2003 Prof. von Keitz began helping trainees identify potential industrial institutions that match trainee's research interest and potential constraints then and make initial contacts with the company if necessary. This mechanism has produced a high rate of success for placing trainees.
Our training program has high industrial relevance, and our trainees are highly regarded by the biotechnology industry.
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The training grant provides not only financial support and an opportunity for cross-disciplinary coursework, but also a wide range of learning experiences outside of the classroom.
Retreats
The students attend annual retreats at the University's station in Itasca State Park.
Exchange Program
The training program has an exchange program with the Nara Institute of Science and Technology. Many trainees visit Japan for a short research exchange.
Multi-Disciplinary Seminars
Trainees attend a formal weekly biotechnology seminar series, which is coordinated and co-sponsored by a number of participating departments and graduate programs. Invited speakers from academia and industry present a variety of research topics covering a wide range of aspects in biotechnology.
Attendance of national conferences/workshops
All trainees are encouraged to attend national and international conferences and workshops in North America to broaden their perspectives. Trainees may receive a small annual travel stipend to use for conference attendance.
Campus workshops, short courses, and symposia
Trainees are invited to attend a variety of workshops, short courses, and symposia and organized on the campus and present poster. Our training program and the NIH training program on chemical biology have been co-organizing a spring workshop. Trainees from both programs jointly organize the technical program.
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Virtually all research, development and even manufacturing in the industrial sector is performed through teams made up of scientists, engineers and other professionals from many different disciplines. This training program provides students with an opportunity to learn to work in such an environment. The Ph.D. graduates from the training program all go on to successful careers. With the high industrial relevance of the training program, trainees are highly regarded by the biotechnology industry.
The graduates from our training program have developed successful careers in industry or academia. Some companies that our graduates are employed at are:
3M, Abbott Laboratories, ACERA, Inc., Advanced Tissue Sciences, Amgen, Ariad Pharmaceuticals, Bayer Corp., Bristol-Myers Squibb, Cargill, Cargill-Dow, Chiron Corp., CA, Dow AgroSciences LLC, Dow Chemical, Dupont, Eli Lilly, Fairview Hospital - Minneapolis, Genencor International, General Mills, H.B. Fuller Co, Kelco Biopolymers, Kosan Biosciences, Merck & Co., PanVera Corporation, Pfizer, Schering-Plough, Scripps, SmithKline Beecham, Tanox, Inc., USDA, Waters, Inc.
A number have entered academic careers and are currently teaching at: Montana State University , Bozeman; State University of New York; and the University of California-Davis
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Contact Us
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Program Director
Prof. Wei-Shou Hu
257Amundson Hall
151 Washington Ave SE
Minneapolis, MN 55455
612-626-7630
wshu@cems.umn.edu
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Program Administrator
Kristi Iskierka
240 Gortner Labs
1479 Gortner Ave.
St. Paul, MN 55108
612-624-3489
iskie001@umn.edu
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Co-Program Director
Prof. Rob Brooker
Genetics and Cell
Development Rm 6-160
321 Church St SE
Minneapolis, MN 55455
612-624-3053
brook005@umn.edu
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Co-Program Director
Prof. Mike Sadowsky
Soil Water and Climate
Room 439 BorH 6028
1991 Upper Buford Circle
St Paul, MN 55108
612-624-2706
sadowsky@umn.edu
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Program Internship Coordinator
Marc von Keitz
Room 240 GorL 6106
1479 Gortner Ave
St Paul, MN 55108
612-624-6758 or 612-624-6774
vonkeitz@umn.edu |
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