Natural product biosynthesis, evolutionary and rational protein design.
Claudia Schmidt-Dannert is interested in microorganisms and plants that naturally synthesize a diversity of chemical compounds useful as drugs, new biomaterials and in food applications.
Taking advantage of advances in genome sequencing, Schmidt-Dannert has screened a multitude of genes from microorganisms and plants for new biosynthetic functions. In doing so, she is fitting microbial cells with new biosynthetic abilities using metabolic and genetic pathway engineering strategies together with evolutionary and rational protein engineering strategies to alter and study biosynthetic activities.
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